
Pressly starred as "Violet" in the 1997 film Poison Ivy: The New Seduction. In 1998 she starred as "Nikki" on the short-lived TV series "Push", and also played a recurring role as the assassin Mika in the TV action series Mortal Kombat: Conquest. From 1999 to 2001, Pressly starred as "Audrey" on the drama series Jack and Jill.
Pressly starred in the independent film Poor White Trash, playing scheming gold-digger Sandy Lake. She subsequently appeared in a number of films, including Not Another Teen Movie (playing Priscilla, a high school cheerleader) and Torque, as a crazed, motorcycle-riding criminal.


In 2005, Pressly was cast in the NBC sitcom My Name Is Earl, as Joy Turner. In 2007 she won the Emmy Award for Outstanding Supporting Actress in a Comedy Series for her work on the show. She has also been nominated for several other awards.
Pressly sang "Fever" in an appearance with the band The Pussycat Dolls. She has also appeared in a number of music videos, including "Girls of Summer" by Aerosmith and the Marilyn Manson cover of "Tainted Love". On May 31, 2006, she hosted the first annual VH1 Rock Honors.
